Does lack of copper trigger CJD?
For someone like me with a family full of dead fCJD victims, I wonder every day what the trigger is. Does something trigger CJD? Or does a lack of something trigger CJD? Here’s a great new study out of North Carolina State University that says a lack of copper can contribute to the misfolding of prions. This is just the kind of stuff that makes my day!
From the Science Blog link above:
“We believe that a prion protein’s normal function is to serve as a copper buffer in the human body, binding with copper ions and keeping those ions from damaging human tissue,” Hodak says. “We wanted to determine whether this was the normal function of the prion, and then look at how that binding affected the prion’s structure.”
To me, the prion’s normal function is to kill my family members. Brilliant scientific minds have the power to change this.
I so look forward to this being solved in my lifetime. To all the great researchers, please keep up the good work. You are ALL my rock stars.
Thank you.
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Dear Heather,
I am the Coordinador (and Founder) of the Mexican CJD Surveillance Center in Mexico. I read about your concern for CJD treatment. Are you attending the CJD2009 meeting in DC? I will be a speaker and will present the nascent Mexican CJD Foundation, established with members of a gCJD family.
I have some relatives in Scottsdale/Chandler and sometimes visit the area, perhaps one day we can meet, either there or in DC.
Regards,
Dr. Victor Sanchez.
Hi Dr. Sanchez,
I did see you were on the list of participants for the CJD Family Conference in DC this year. I won’t be able to make it, but would love to meet up with you the next time you’re in the area. It would be interesting to get the Mexican perspective on CJD and see what is happening with it in your country. What is gCJD? I’ve heard of sCJD, iCJD, vCJD, nvCJD, and probably a couple others aside from obviously fCJD, but what is gCJD?
Heather Larson