What codon 129 does

Dr. Brian Appleby posted an interesting blog this morning about genetic susceptibility to kuru.  I thought it was interesting to learn more about what codon 129 is responsible for since wee see this on our NPDPSC autopsy paperwork.  As someone who lost a mother at age 56 to fCJD, I thought it was interesting to learn that codon 129 affects age of onset of the disease.  I’ll have to find my mom’s paperwork, because I can’t remember what she was on codon 129.